CaffeineĬaffeine is the most commonly consumed psychoactive substance in the world ( 20). Green coffee bean extract may cause modest weight loss, but keep in mind that many of the studies that have found this have been industry-sponsored. The chlorogenic acid it contains may also cause diarrhea, and some people may be allergic to green coffee beans ( 19). Side effects: It can cause the same side effects as caffeine. It is also high in antioxidants ( 15, 16, 17, 18). Other benefits: Green coffee bean extract may help lower blood sugar levels and reduce blood pressure. How it works: Caffeine can increase fat burning, and chlorogenic acid can slow the breakdown of carbohydrates in the gut.Įffectiveness: Several human studies have shown that green coffee bean extract could help people lose weight ( 12, 13).Ī meta-analysis of all the current randomized control trials on green coffee bean extract’s effect on obesity found that the supplement has a significant impact on minimizing body mass index ( 14). They contain two substances believed to help with weight loss: caffeine and chlorogenic acid. Green coffee beans are simply coffee beans that haven’t been roasted. More research is needed to determine effectiveness and safety concerns. There are few large-scale studies on this supplement and no data on its long-term effectiveness. Hydroxycut products were removed from shelves as a result of cardiovascular risks in 2004 and hepatotoxicity in 2009 ( 10).Īcute liver injury has also been connected with using Hydroxycut supplements ( 11). Side effects: If you are sensitive to caffeine, you may experience anxiety, jitteriness, tremors, nausea, diarrhea, and irritability ( 9). canephora robusta, or green coffee extract, one of the key ingredients in Hydroxycut, led to about a 5.5-pound (2.47-kg) weight loss compared to the placebo ( 8). How it works: It contains several ingredients claiming to help with weight loss, including caffeine and a few plant extracts such as green coffee extract, which we’ll talk more about later.Įffectiveness: A 2011 meta-analysis of five clinical trials found that supplementation with C. The brand makes several products, but the most common is simply called “Hydroxycut.” Hydroxycut has been around for more than a decade and is one of the most popular weight loss supplements in the world. SummaryĮven though garcinia cambogia may contribute to modest weight loss, the effects are quite small and may not be noticeable. Side effects: While it’s widely agreed that garcinia cambogia is safe to take in recommended amounts, studies within the last few years have pointed to some serious side effects.Ī 2018 study documented four cases of women who experienced acute liver failure after taking weight loss supplements containing garcinia cambogia ( 5).Īdditionally, hepatotoxicity, or liver impairment, and some episodes of mania have also been reported in conjunction with taking garcinia cambogia ( 6, 7). In a total of 54 randomized controlled trials in healthy adults with overweight or obesity, the authors found no difference in weight or body fat percentage between the garcinia cambogia group and the placebo group ( 3).Ī 2020 review that looked at eight trials on garcinia cambogia found that, on average, it caused weight loss of about 3 pounds (1.34 kg) ( 4). How it works: Animal studies show that it can hinder a fat-producing enzyme in the body and increase serotonin levels, potentially helping to reduce cravings ( 1, 2).Įffectiveness: In one meta-analysis, researchers explored four electronic research databases to investigate the effectiveness of herbal medicines, including garcinia cambogia. The fruit’s skin contains hydroxycitric acid, the active ingredient in garcinia cambogia extract, which is marketed as a diet pill. It’s a small, green fruit shaped like a pumpkin. Garcinia cambogia became popular worldwide after being featured on “The Dr.
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